NovaBioX® Croscarmellose Sodium CAS 74811-65-7
(Superdisintegrant Excipient)
Chemical Name: Croscarmellose Sodium
CAS No.: 74811-65-7
Croscarmellose Sodium is a internally cross-linked sodium carboxymethylcellulose, serving as a disintegrant in pharmaceutical formulations. It appears as a white or off-white, free-flowing powder with high purity and excellent water absorption. Its cross-linked network structure prevents gel layer formation, enabling rapid wicking and swelling. This unique swelling action generates sufficient hydrodynamic pressure to rupture tablets or capsules, promoting fast drug release.
Item | Specification |
Appearance | White or greyish-white, hygroscopic powder |
Loss on drying | ≤10.0% |
Water-soluble substance | ≤10.0 % |
Sodium chloride and sodium glycolate | ≤0.5% |
pH | 5.0-7.0 |
Settling volum | 10.0 ml-30.0ml |
Degree of substitution | 0.60-0.85 |
Sulfated ash | 14.0%-28.0% |
Microbial contamination | Tymc: acceptance criterion 10²CFU/g |
Tamc: acceptance criterion 103 CFU/g |
Disintegrant for tablets and capsules; also used as suspending agent and absorbent in food and cosmetic products.
Packaging: 25kgs/drum.
Storage:
Being kept in dry, clean warehouse with well ventilation.
Avoid exposing to light and heating.
Protecting the product from leakage, rain and insolation during transportation.
Q1. What is another name for Croscarmellose Sodium?
A: Croscarmellose Sodium is also known as Crosslinked Sodium Carboxymethyl Cellulose and is widely recognized as a superdisintegrant in pharmaceutical manufacturing.
Q2. What are the main uses of Croscarmellose Sodium?
A: It is widely used in tablets, capsules, nutraceutical products and other oral solid dosage forms to improve tablet disintegration and formulation performance.
Q3. Are there any side effects of Croscarmellose Sodium?
A: For the vast majority of consumers, croscarmellose sodium causes no side effects or health risks. It is a non-toxic, non-irritating ingredient that is not absorbed by the human body; it passes through the digestive tract completely unchanged. Because it is used at extremely low concentrations (typically 1.0% - 4.0%) in individual tablets, it is globally recognized as safe (GRAS) by the FDA and EFSA for both pharmaceutical drugs and daily dietary supplements.
Q4: Where can I buy bulk pharmaceutical-grade Croscarmellose Sodium at wholesale factory pricing?
A: You can source high-purity, multi-ton quantities of premium Croscarmellose Sodium directly from verified B2B pharmaceutical ingredient manufacturers. Our brand NovaBioX® Croscarmellose Sodium guarantees strict compliance with USP/EP standards, ultra-low heavy metals, and stable batch-to-batch consistency. Contact our sales desk today to receive a current spot price quote or to request a free regulatory testing sample!
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